mice
mice can finally predict, not just estimate, from multiply imputed data.
A side-by-side editorial comparison of goat and PEIMAN2 — release velocity, themes, recent moves, and the top alternatives to consider.
A gene-set enrichment package that outgrew its human-only origins, then went quiet.
GOAT is a CRAN-published R package for gene set enrichment testing, now at 1.1.4. The visible arc runs from a 2024 beta through a first public CRAN release to a 1.1 line that broadened the package past human gene sets and added persistence for completed analyses. Recent releases are small: the newest ships an igraph handle on plot_network() plus bug fixes.
PEIMAN2 cut its annotation database loose from its release cycle without breaking CRAN.
PEIMAN2 does enrichment analysis over post-translational modifications, testing whether a protein list is enriched for particular PTMs against UniProt-derived annotations, with translation functions bridging to mass spectrometry workflows. Its answers are only as current as its bundled database, and until June that database could only be refreshed by releasing a new package version. Version 1.1.0 changes that.
GOAT is a CRAN-published R package for gene set enrichment testing, now at 1.1.4. The visible arc runs from a 2024 beta through a first public CRAN release to a 1.1 line that broadened the package past human gene sets and added persistence for completed analyses. Recent releases are small: the newest ships an igraph handle on plot_network() plus bug fixes.
The substantive expansion happened in the 1.1 cycle; everything since has been maintenance and plotting ergonomics. Each release since 1.1 touches one function and returns something callers previously had to reconstruct, which reads as a package settling into a stable API and responding to individual user requests rather than pursuing new scope. The 13-month gap between 1.1.2 and 1.1.4 puts it firmly in low-cadence maintenance.
Expect continued point releases that expose internals from the plotting functions or refresh the bundled GO release, not new analysis capability. The entries give no signal of a planned 1.2.
PEIMAN2 does enrichment analysis over post-translational modifications, testing whether a protein list is enriched for particular PTMs against UniProt-derived annotations, with translation functions bridging to mass spectrometry workflows. Its answers are only as current as its bundled database, and until June that database could only be refreshed by releasing a new package version. Version 1.1.0 changes that.
The package has been moving from a fixed snapshot toward versioned, user-selectable data. Earlier releases updated the bundled database in place — 1.0.0 shipped the March 2025 version and said little else — which meant the annotation vintage was whatever the package version implied. Now update_peiman_database() downloads and caches external database files and UniProt PTM lists, enrichment workflows take a database_version argument, and the mass-spec translators take a ptmlist_version, so an analysis can pin a dated database rather than a package release. The CRAN-safe default is preserved deliberately: loading, examples and checks still use the bundled internal data and need no network.
Version pinning is now expressible but the release notes do not describe how a chosen version is recorded in output, so surfacing the active database version in results is the natural companion. The database and the UniProt PTM list are versioned separately, which leaves room for a combined manifest.
Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either goat or PEIMAN2.
mice can finally predict, not just estimate, from multiply imputed data.
A market-microstructure toolkit that keeps adding estimators as the papers land.
A vowel-analysis package trimming dependencies after an email address got it archived.
The R half of the EMU speech database system, fixing what was quietly broken.
A Bayesian model-averaging package spending its 2.0 on memory, not methods.
tidyplots keeps rebuilding its own foundations rather than layering around them.
See all goat alternatives → · See all PEIMAN2 alternatives →
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
They serve adjacent needs but don't currently overlap on shipped themes. goat and PEIMAN2 are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. goat and PEIMAN2 are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.
Top goat alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "goat alternatives" section above for the current picks, or visit /alternatives/goat for the full list with editorial commentary on each.
Top PEIMAN2 alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "PEIMAN2 alternatives" section above for the current picks, or visit /alternatives/peiman2 for the full list with editorial commentary on each.