Grafana Mimir vs RMVMR

RMVMR provides radial multivariable Mendelian randomization — radial IVW estimation and plots layered over the MVMR package's conditional instrument-strength machinery. It has no independent release schedule: versions arrive alongside MVMR's, pin a minimum MVMR version, and fix defects in the seam between the two. Its most recent release landed the same day as new versions of MVMR and OneSampleMR.

The work is code hygiene with results held fixed. ivw_rmvmr() now fits the radial IVW model explicitly rather than inheriting variables left over from the orientation loop, an undocumented data element carrying unused intermediate frames is gone, and plot_rmvmr() stops recomputing univariate radial analyses it already has — roughly halving the RadialMR calls with identical output. Each note is explicit that coefficients, standard errors and degrees of freedom are unchanged, which is a deliberate contrast with MVMR's own 2026 releases, where several fixes did change reported values.

Because the package pins MVMR versions rather than vendoring behaviour, the next release most likely follows MVMR's next correctness fix; nothing in the notes points to independent feature work.