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Comparison · Analytics
OneSampleMR vs silx
A side-by-side editorial comparison of OneSampleMR and silx — release velocity, themes, recent moves, and the top alternatives to consider.
OneSampleMR vs silx: at a glance
What is OneSampleMR?
OneSampleMR found that argument order in a formula was silently changing its estimates
OneSampleMR implements one-sample Mendelian randomization estimators — two-stage predictor substitution, two-stage residual inclusion, and Sanderson-Windmeijer conditional F statistics for instrument strength. The package spent its first years on packaging and dependency upkeep. The 2026 releases turn to substance: broader support for models fitted elsewhere, then a correctness fix for a defect that depended on nothing more than where covariates appeared in a formula.
What is silx?
silx settles into maintenance a release after its PySide6 migration
silx is in the quiet phase after a generational release. 3.1.1 is a single fix to FitWidget loading a fit function from file. The release before it, 3.1.0, was the first real feature work since the migration - asinh axis scaling, twilight colormaps, and dark-theme icons - and 3.0.1 was similarly small. The 3.0.0 cut that reset the Qt binding and Python floor still defines what the line is doing.
OneSampleMR vs silx: editorial side-by-side
OneSampleMR
0.0ANALYTICS
OneSampleMR found that argument order in a formula was silently changing its estimates
◆ Current state
OneSampleMR implements one-sample Mendelian randomization estimators — two-stage predictor substitution, two-stage residual inclusion, and Sanderson-Windmeijer conditional F statistics for instrument strength. The package spent its first years on packaging and dependency upkeep. The 2026 releases turn to substance: broader support for models fitted elsewhere, then a correctness fix for a defect that depended on nothing more than where covariates appeared in a formula.
◆ Where it's heading
Two threads. The first is reach — fsw() now reads models fitted by AER::ivreg(), estimatr::iv_robust() and fixest::feols() in addition to ivreg::ivreg(), which makes conditional F statistics available without refitting in the package's own idiom. The second is hardening: clear errors when more than one exposure is given or when a variable collides with the reserved name y, and print methods that no longer fail on user-specified t0 with log or logit links. Both come largely from user reports rather than a plan.
◆ Prediction
The estimator-support work has been adding one IV-fitting package at a time on outside contributions, so further backends are the likeliest next content — the package's own estimators have been stable since first release.
silx
5.0ANALYTICS
silx settles into maintenance a release after its PySide6 migration
◆ Current state
silx is in the quiet phase after a generational release. 3.1.1 is a single fix to FitWidget loading a fit function from file. The release before it, 3.1.0, was the first real feature work since the migration - asinh axis scaling, twilight colormaps, and dark-theme icons - and 3.0.1 was similarly small. The 3.0.0 cut that reset the Qt binding and Python floor still defines what the line is doing.
◆ Where it's heading
The cadence has slowed markedly since April, and the content has shifted from structural change to plotting and colormap refinement. That is the expected shape after a binding migration: downstream beamline code needs a stable target, so the project trades feature velocity for a quiet surface. The gap between 3.0.1 in May and 3.1.0 in August is the clearest signal of the deliberate slowdown.
◆ Prediction
Expect further point releases servicing the plotting and fitting widgets rather than another structural change, with feature work continuing to arrive in the 3.1.x minors rather than patches.
Alternatives to OneSampleMR and silx
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either OneSampleMR or silx.
aniread
aniread stops asking you to know which tracker wrote the file
Rho
Rho's release machinery finally produced a stable build — and it shipped no new product.
Usermaven
Usermaven closed the loop: data comes in from anywhere, and now it goes back out.
OpenCTI
OpenCTI spends a release unblocking queues and hardening upserts
Grafana Mimir
Mimir's feed is a weekly Helm bot, with the 3.2 candidate the only real release in months
See all OneSampleMR alternatives → · See all silx alternatives →
Recent activity from OneSampleMR and silx
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 3h agosilxFitWidget fix for loading a fit function from file
- 9d agosilx3.1.0: asinh axis scaling, twilight colormaps, dark-theme icons
- 1mo agoOneSampleMROneSampleMR fixes estimates broken by covariate order in the formula
- 3mo agosilx3.0.1: silx view fails to disable HDF5 file locking
- 3mo agosilx3.0.0: PySide6 becomes the default Qt binding, Python 3.10 required ⚡
- 3mo agosilx3.0.0rc1: release candidate for the PySide6 migration
- 5mo agoOneSampleMROneSampleMR computes conditional F for three more IV packages
- 1y agoOneSampleMROneSampleMR 0.1.6
- 1y agosilx2.2.2: plot axes limits, OpenGL axes and libhdf5 1.14 fixes
- 2y agoOneSampleMROneSampleMR 0.1.5
- 2y agoOneSampleMROneSampleMR 0.1.4
- 3y agoOneSampleMROneSampleMR 0.1.3
Frequently asked questions
What is the difference between OneSampleMR and silx?
They serve adjacent needs but don't currently overlap on shipped themes. silx is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is OneSampleMR better than silx?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. silx is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to OneSampleMR?
Top OneSampleMR alternatives in Analytics are ranked by recent ship velocity. Browse the "OneSampleMR alternatives" section above for the current picks, or visit /alternatives/onesamplemr for the full list with editorial commentary on each.
What are the best alternatives to silx?
Top silx alternatives in Analytics are ranked by recent ship velocity. Browse the "silx alternatives" section above for the current picks, or visit /alternatives/silx for the full list with editorial commentary on each.