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Comparison · Infra & APIs
campsis vs PowerTOST
A side-by-side editorial comparison of campsis and PowerTOST — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:pharmacometrics
campsis vs PowerTOST: at a glance
What is campsis?
Campsis breaks its API on purpose: snake_case throughout, RxODE compatibility cut loose.
Campsis runs clinical-trial simulations from pharmacometric models, sitting on mrgsolve and rxode2 as interchangeable engines, with the sibling package Campsismod supplying the model object layer. Version 1.9.0 is the release where the suite stops carrying its history: the whole API migrates to snake_case, backward compatibility with the old RxODE package is removed, and result processing is refactored into output functions that can be applied as a collection, with an NCA table the first substantial one. Campsismod made the same snake_case move a week earlier, so this is a suite-wide rename rather than one package's decision.
What is PowerTOST?
A bioequivalence sample-size workhorse whose news is which regulator it now covers
PowerTOST computes power and sample size for bioequivalence and its changelog reads as a record of regulatory divergence more than statistical development. Version 1.5-3 added the Gulf Co-operation Council as a regulator setting; 1.5-4 and 1.5-6 stripped 'FDA' out of the narrow-therapeutic-index function names once China's CDE began requiring the same evaluation. The most recent release, 1.5-7, is a single fix to how nvec() splits a total sample size across sequences.
campsis vs PowerTOST: editorial side-by-side
campsis
3.8INFRA · APIS
Campsis breaks its API on purpose: snake_case throughout, RxODE compatibility cut loose.
◆ Current state
Campsis runs clinical-trial simulations from pharmacometric models, sitting on mrgsolve and rxode2 as interchangeable engines, with the sibling package Campsismod supplying the model object layer. Version 1.9.0 is the release where the suite stops carrying its history: the whole API migrates to snake_case, backward compatibility with the old RxODE package is removed, and result processing is refactored into output functions that can be applied as a collection, with an NCA table the first substantial one. Campsismod made the same snake_case move a week earlier, so this is a suite-wide rename rather than one package's decision.
◆ Where it's heading
The 1.8 and 1.9 releases together describe a package being made drivable from outside R. JSON interfaces arrived first for models in Campsismod 1.3.0 and for datasets in Campsis 1.8.0, then extended to scenarios, settings and study replication; the output side has now been generalised the same way, from fixed result processing to a collection of output functions applied to simulated results. Renaming every function and cutting RxODE loose is the cost of that consolidation, paid in one deliberate breaking release rather than spread across several.
◆ Prediction
With the rename and the RxODE removal behind it, the next releases should restore the rxode2 engine to the test suite, which 1.9.0 removed temporarily, and continue filling out the output-function catalogue beyond NCA. The JSON surface looks like the intended entry point for driving Campsis from outside R, though the entries do not say what is meant to consume it.
PowerTOST
0.0INFRA · APIS
A bioequivalence sample-size workhorse whose news is which regulator it now covers
◆ Current state
PowerTOST computes power and sample size for bioequivalence and its changelog reads as a record of regulatory divergence more than statistical development. Version 1.5-3 added the Gulf Co-operation Council as a regulator setting; 1.5-4 and 1.5-6 stripped 'FDA' out of the narrow-therapeutic-index function names once China's CDE began requiring the same evaluation. The most recent release, 1.5-7, is a single fix to how nvec() splits a total sample size across sequences.
◆ Where it's heading
The package is in long maintenance with a widening regulatory surface: the statistical methods are settled, and releases arrive when an agency publishes a framework that can be expressed as a settings variant of an existing method. Function naming has been deliberately decoupled from any single agency, with the deprecated FDA-suffixed aliases carried for years before removal. Cadence has slowed to roughly one release every eighteen months.
◆ Prediction
The next release is most likely another regulator setting or a small fix; on the deprecation notice already given, the power.NTIDFDA()-style aliases are the obvious removal candidate.
Alternatives to campsis and PowerTOST
Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either campsis or PowerTOST.
tabular
tabular went from clinical tables to complete TFL output in under two months.
usmapdata
usmapdata ships its 2025 shapefiles on the year-indexed model it adopted in 0.4.0.
glcdp
glcdp reaches 1.0.0 with a stable schema contract behind its data explorer.
prova
prova adds expected-utility calculation on top of its Bayesian inference core.
checkhelper
checkhelper grew from a check wrapper into a CRAN pre-submission auditor.
See all campsis alternatives → · See all PowerTOST alternatives →
Recent activity from campsis and PowerTOST
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 15d agocampsissnake_case across the API; RxODE compatibility removed ⚡
- 5mo agocampsisJSON arguments reach Dataset, Scenarios and Settings
- 7mo agocampsisMaintenance release for future package warnings
- 7mo agocampsisJSON import for Campsis datasets
- 10mo agoPowerTOSTFix for splitting total sample size across sequences
- 1y agocampsisDosing gains vectorized compartments and cycle repetition
- 1y agocampsisParameter uncertainty from SIR and bootstrap output
- 2y agoPowerTOSTNTID functions renamed off the FDA acronym; GCC guidance in vignettes
- 4y agoPowerTOSTpower.NTID() aliases added; FDA-suffixed names deprecated
- 5y agoPowerTOSTGulf Co-operation Council added as a regulator setting
- 5y agoPowerTOSTMaintenance release with vignette and documentation clarifications
- 5y agoPowerTOSTstringsAsFactors fix for older R in a vignette example
Frequently asked questions
What is the difference between campsis and PowerTOST?
Both compete on the same themes — pharmacometrics — within Infra & APIs. campsis is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is campsis better than PowerTOST?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. campsis is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.
What are the best alternatives to campsis?
Top campsis alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "campsis alternatives" section above for the current picks, or visit /alternatives/campsis for the full list with editorial commentary on each.
What are the best alternatives to PowerTOST?
Top PowerTOST alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "PowerTOST alternatives" section above for the current picks, or visit /alternatives/powertost for the full list with editorial commentary on each.